publications
Representative publications (before IISc)
(these should give you an idea of the NMR methods we routinely employ in the lab)
1) Rosenzweig R*, Sekhar A*, Nagesh J and Kay L E "Promiscuous binding by Hsp70 results in conformational heterogeneity and fuzzy chaperone-substrate ensembles" (2017) eLife, 6, e28030. (* equal contributors and joint corresponding authors) Link
2) Sekhar A, Rumfeldt J A O, Broom H R, Doyle C M, Sobering R E, Meiering E M and Kay L E "Probing the free energy landscapes of ALS disease mutants of SOD1 by NMR Spectroscopy" (2016) Proc. Natl. Acad. Sci. U.S.A., 113, E6939-E6945. Link
3) Sekhar A*, Rosenzweig R*, Bouvignies G and Kay L E "Hsp70 biases the folding pathways of client proteins" (2016) Proc. Natl. Acad. Sci. U.S.A., 113, E2794-E2801. (* equal contributors) Link
4) Sekhar A*, Rosenzweig R*, Bouvignies G and Kay L E "Mapping the conformation of a client protein through the Hsp70 functional cycle" (2015) Proc. Natl. Acad. Sci. U.S.A., 112, 10395-10400. (* equal contributors and joint corresponding authors) Link
5) Sekhar A, Rumfeldt J A O, Broom H R, Doyle C M, Bouvignies G, Meiering E M and Kay L E "Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways" (2015) eLife, 4, e07296. (joint corresponding author) Link
6) Sekhar A and Kay L E "NMR paves the way for atomic level descriptions of sparsely populated, transiently formed biomolecular conformations" (2013) Proc. Natl. Acad. Sci. U.S.A., 110, 12867-12874. (Review) Link
7) Sekhar A*, Vallurupalli P* and Kay L E "Defining a length scale for millisecond-timescale protein conformational exchange" (2013) Proc. Natl. Acad. Sci. U.S.A., 110, 11391-11396. (* joint corresponding authors) Link
For Ashok's full list of publications, please click here.
Link to Ashok's google scholar profile.
